Effect of Fluoride Varnish application on Primary Dentition among Preschool Children in Dharan: A Randomized Controlled Trial

Introduction: Topical application of fluoride varnish on the tooth surface prevents dissolution rates materials and increases re-precipitation lost minerals. Objective: To assess effectiveness in primary dentition among preschool children at high risk dental caries. Methods: A randomized controlled trial was conducted with two parallel-group, comprising 3–5-year-old children, 100 each group (Fluoride or Placebo varnish). Dental caries were recorded baseline, three- six-month using Caries Assessment Treatment Instrument (CAST) scoring system. Statistical analysis done Chi-square test for categorical data, Mann-Whitney U test, independent t-test, Wilcoxon Signed Ranks quantitative data. The level significance set p<0.05. Results: Overall, progression from baseline to three months six more placebo than (38.98% 31.3% respectively). proportion new lesions that every interval. difference between groups statistically significant (p<0.05). Fluoride treatment once had a better effect preventive fraction 62.1% comparison (59.0%). Conclusions: can be prevented effectively by use 5% sodium varnish. is efficacious when applied twice year